Principal Scientist - Non Clinical PKPD

This is an opportunity to join a successful biopharmaceutical company, delivering novel solutions to a range of disease areas. Using integrated PKPD, modelling, and DMPK approaches you will drive smarter drug development — from target ID to first in human clinical trials. We’re looking for an experienced scientist to lead non-clinical PKPD strategy, working across study design, data analysis, and regulatory submissions to help bring new therapies to patients. Responsibilities: Lead design and execution of non-clinical PKPD and GLP toxicokinetics studies Analyse data using Phoenix WinNonLin, Berkeley Madonna and R Produce clear reports and regulatory-standard documentation Collaborate with internal teams and CROs to deliver high-quality, compliant data Communicate results effectively to scientific and project stakeholders Ideal Profile: PhD/MSc/BSc in relevant discipline, 5 years’ PKPD analysis experience in pharma/CRO Strong understanding of pharmacology and drug action Proven track record in regulatory-standard study design and reporting inc. strong experience with WinNonLin Excellent communication skills and ability to work in a matrix environment Organised, proactive, and able to manage multiple projects Day to day responsibilities can be carried out either onsite or at home with a requirement for the job holder to be onsite at least 2 days/week. The role is offered on an initial 12 month contract basis with realistic potential for extension. Apply to VRS today! Keywords: PK, PD, pharmacokinetics, pharmacodynamics, pharmacology, DMPK, metabolism, pharmaceutical, toxicology, WinNonLin, Berkshire, Reading, Slough, London, VRS9114SE

Location: Slough, UK, GB

Posted Date: 8/23/2025