Ph.d. Fellow in Synthetic Biology (Id : 24000050)

Italy In order to be admitted into the ARC program, the minimum requirements are: i. a Masters-level degree, which broadly corresponds to a 4 / 5-year undergraduate MSc / MChem / Meng-style degree or to a postgraduate Masters in the British system, or to a second level University degree in Italy; ii. where English is not the applicant’s first language, a valid IELTS (International English Language Testing System) certificate. The minimum acceptable score is an overall 6.5, with no less than 6.0 in any of the four categories. Two PhD fellow positions will be available from October 1st, 2024 in the group of Synthetic and Systems Biology for Biomedicine led by Dr. Velia Siciliano Title of the project: Engineering immune cells for better tumor treatment. Background: The treatment of solid tumours remains challenging, with poor outcomes. The tumor microenvironment (TME) is strongly immune-suppressive, leading to the skewing of the cytotoxicity capacity of immune cells. Therefore, there is a pressing need for therapeutic interventions to transform cold tumours into hot tumours. Description: Synthetic biology offers the potential to engineer immune cells that can reverse cold tumours and establish novel methods of killing cancer cells. The project aims to establish genetic circuits that regulate interactions between immune and cancer cells and modify the TME. Main Supervisor: Velia Siciliano (Synthetic and Systems Biology for Biomedicine) Essential expertise: i. Bioengineering ii. Synthetic Biology iii. Immunology iv. Molecular Biology Desirable expertise: i. Cancer Biology ii. Cell Biology How to apply: Prospective students must submit the following documents via the online form: 2-page CV including studies, expertise, and achievements 1-page research statement with project choice and justification Transcript of undergraduate and postgraduate studies A valid IELTS certificate obtained within the last two years Contact details of two referees Istituto Italiano di Tecnologia is an Equal Opportunity Employer that actively seeks diversity in the workforce. Please note that the data provided will be used solely for professional profile evaluation and selection, in compliance with data protection laws. Data will be processed by Istituto Italiano di Tecnologia, Genoa, Via Morego 30, as Data Controller. J-18808-Ljbffr

Location: Napoli, Campania, IT

Posted Date: 8/22/2025