European HEOR & RWE Director

Director, Real-World Evidence & Health Economic Outcomes Location: London (Hybrid or Office-based) Type: Full-time We are recruiting for an experienced and strategic leader to take on a pivotal role in real-world evidence generation and health economic outcomes within a dynamic and purpose-driven life sciences organisation. This position reports to the Head of Patient Access and is responsible for leading the development and execution of an international evidence-generation programme focused on a rare disease area, with an initial emphasis on data collection from Centres of Expertise across Europe. The successful candidate will ensure the programme is fully integrated into broader evidence-generation efforts, with a critical role in shaping health economics strategies to support regulatory, HTA, and payer engagement across key European territories. Key Responsibilities: Lead the strategy, planning and operational execution of a rare disease Real-World Evidence programme, ensuring alignment with internal and external stakeholders Manage delivery in partnership with an external CRO to meet programme timelines and budget Cultivate strong working relationships with expert treatment centres across Europe; oversee collaborations through one-to-one engagement and programme-level governance (e.g., Steering Committees) Act as the operational lead for evidence generation partnerships, ensuring coordination across internal cross-functional teams and external scientific partners Identify and onboard additional potential participating centres; support the development of data analysis strategies and outputs Lead or support the publication of key data outputs and present findings in external forums to further stakeholder engagement and understanding Work closely with regulatory and market access functions to co-develop the programme alongside data customers such as HTA bodies and payers Contribute to the development of health economic models and value propositions; support interactions with pricing and reimbursement authorities Ensure seamless integration of the Real-World Evidence programme into broader Medical Affairs and Evidence Generation strategy Build strong, respectful partnerships with advocacy organisations and relevant stakeholders within the rare disease community Collaborate effectively with alliance or industry partners to deliver programme objectives as part of a shared initiative Candidate Profile: 7–10 years of experience in Real-World Evidence, health economics, registries, or related functions within pharma or biotech Advanced degree in health economics, public health, pharmaceutical sciences, or a related field (or equivalent experience) Strong knowledge of real-world data sources and analytical approaches Familiarity with patient-reported outcomes (PROs), economic modelling, and value demonstration to payers/HTAs is highly advantageous Proven ability to manage complex, multi-stakeholder projects across geographies High emotional intelligence, excellent relationship-building skills, and the ability to influence across functions Entrepreneurial mindset with a proactive, solutions-focused approach Demonstrated commitment to addressing unmet medical needs in a meaningful way What’s on Offer: Competitive salary Comprehensive benefits package Opportunity to drive real impact in a high-need therapeutic area Collaborative and mission-driven working environment

Location: City of London, London, GB

Posted Date: 7/13/2025